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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGIR
All Species:
8.79
Human Site:
S375
Identified Species:
24.17
UniProt:
P43119
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43119
NP_000951.1
386
40956
S375
G
S
A
V
G
T
S
S
K
A
E
A
S
V
A
Chimpanzee
Pan troglodytes
Q95KZ0
490
53285
S432
L
A
Q
E
D
T
T
S
L
R
T
L
R
I
S
Rhesus Macaque
Macaca mulatta
XP_001112077
386
41030
S375
G
S
T
V
G
A
S
S
K
A
E
A
N
V
A
Dog
Lupus familis
XP_541544
384
40823
K374
S
T
V
G
A
S
S
K
V
G
S
A
A
A
C
Cat
Felis silvestris
Mouse
Mus musculus
P43252
415
44444
M402
G
D
G
C
S
V
G
M
P
S
K
S
E
A
I
Rat
Rattus norvegicus
P43253
416
44644
M403
G
D
G
C
S
V
G
M
P
S
K
T
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001076834
356
39247
T345
R
Q
D
S
Q
C
P
T
S
A
K
T
K
L
E
Frog
Xenopus laevis
NP_001084446
371
41878
D360
S
S
Q
K
S
Q
P
D
D
H
D
K
I
P
P
Zebra Danio
Brachydanio rerio
XP_689903
364
40815
S352
A
E
D
I
K
H
S
S
S
I
Q
S
K
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.6
96.6
83.4
N.A.
73.9
73.8
N.A.
N.A.
43.7
38.5
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.9
97.4
88
N.A.
78.5
77.6
N.A.
N.A.
57.7
57.7
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
80
13.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
86.6
33.3
N.A.
26.6
20
N.A.
N.A.
26.6
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
0
12
12
0
0
0
34
0
34
12
34
23
% A
% Cys:
0
0
0
23
0
12
0
0
0
0
0
0
0
0
12
% C
% Asp:
0
23
23
0
12
0
0
12
12
0
12
0
0
0
0
% D
% Glu:
0
12
0
12
0
0
0
0
0
0
23
0
23
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
45
0
23
12
23
0
23
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
12
0
0
12
23
12
% I
% Lys:
0
0
0
12
12
0
0
12
23
0
34
12
23
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
12
0
0
12
0
12
0
% L
% Met:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
23
0
23
0
0
0
0
12
12
% P
% Gln:
0
12
23
0
12
12
0
0
0
0
12
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% R
% Ser:
23
34
0
12
34
12
45
45
23
23
12
23
12
0
12
% S
% Thr:
0
12
12
0
0
23
12
12
0
0
12
23
0
0
0
% T
% Val:
0
0
12
23
0
23
0
0
12
0
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _